Did you create the server before or after installing TPTP. If before, try creating a new server and see if profiling is enabled on the new server.
Wait a minute. The server is running, no wonder the Profile button is disabled! Stop the server first. (The Profile button is really a "run with profiler" button.)
Thanks peter I've resolved
when creating a new server I have to select Jboss/Jboss v4.2 instead of Jboss, a division of RedHat/Jboss AS 4.2
That's a reference image if someone has the same stupid problem
The "JBoss, a division of RedHat" comes from JBoss Tools. You might ask on the JBoss Tools forum (http://www.jboss.org/index.html?module=bb&op=viewforum&f=201) about support for profiling when using JBoss Tools.