We were experiencing intermittent hangs in IE with 2.1.1 GA and commented out the setTimeout in remote.js (jboss-seam-remoting.jar).
Not sure if this goes into your JIRA queue:
asyncReq = new ActiveXObject("Microsoft.XMLHTTP");
var rcb = Seam.Remoting.requestCallback;
asyncReq.onreadystatechange = function() {
if (rcb) rcb(asyncReq, callback);
}
/*
window.setTimeout(function() {
asyncReq.onreadystatechange = function() {
if (rcb) rcb(asyncReq, callback);
}
}, 0);
*/