If it is an InOut jms message, it should have "JMSReplyTo" in it's headers to point to reply queue and camel will sent out message to this replyTo queue. Otherwise, you could add "?replyTo=" option to the jms endpoint uri to explicitely specify a replyTo queue. However, you probably need to make sure you have "JMSCorrelationID" in it's header so you can correlate the response message with request message.
Thnx. It worked.