Michael, this is a JBoss Messaging DESIGN forum, not a JBossMQ USER forum.
To answer you question, yes, it is possible to create topics at runtime, look at the JMSDestinationManager's JMX interface.
Please post further user questions on http://jboss.org/index.html?module=bb&op=viewforum&f=48
My Appologies. thanks for the direction.