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To my knowledge, XA transactions work as long as Infinispan integrates correctly with a transaction manger.
I have no idea how/if this is supposed to work in EAP 5 though (IIRC we did test this with EAP 6 and Wildfly as part of [MODE-1498] Support JTA transactions - JBoss Issue Tracker).
Also, you need to be aware that even if ISPN integrated correctly with the Tx Manager, Infinispan 5 does not support XA at a cache-store level. So XA will probably work only for the in-memory caches. See this: https://firstname.lastname@example.org/msg06426.html and [ISPN-604] Re-design CacheStore transactions - JBoss Issue Tracker for more information about that.